Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo

Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo

Monocytes can develop into dendritic cells (DCs) that migrate to lymph nodes (LNs) and present antigens to T cells. However, we find that this differentiation is blocked when monocytes accumulate subcutaneously in response to bacteria or lipopolysaccharide (LPS). The inhibition of DC differentiation...

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Bibliographic Details
Main Authors: Rotta, Gianluca, Edwards, Emmerson W., Sangaletti, Sabina, Bennett, Clare, Ronzoni, Simona, Colombo, Mario P., Steinman, Ralph M., Randolph, Gwendalyn J., Rescigno, Maria
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194237/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194237/

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