Two Distinct Pathways Leading to Nuclear Apoptosis

Two Distinct Pathways Leading to Nuclear Apoptosis

Apaf-1−/− or caspase-3−/− cells treated with a variety of apoptosis inducers manifest apoptosis-associated alterations including the translocation of apoptosis-inducing factor (AIF) from mitochondria to nuclei, large scale DNA fragmentation, and initial chromatin condensation (stage I). However, whe...

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Main Authors: Susin, Santos A., Daugas, Eric, Ravagnan, Luigi, Samejima, Kumiko, Zamzami, Naoufal, Loeffler, Markus, Costantini, Paola, Ferri, Karine F., Irinopoulou, Theano, Prévost, Marie-Christine, Brothers, Greg, Mak, Tak W., Penninger, Josef, Earnshaw, William C., Kroemer, Guido
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193229/

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