Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

A number of diseases are due to lysosomal destabilization, which results in damaging cell loss. To investigate the mechanisms of lysosomal cell death, we characterized the cytotoxic action of two widely used quinolone antibiotics: ciprofloxacin (CPX) or norfloxacin (NFX). CPX or NFX plus UV light (N...

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Bibliographic Details
Main Authors: Boya, Patricia, Andreau, Karine, Poncet, Delphine, Zamzami, Naoufal, Perfettini, Jean-Luc, Metivier, Didier, Ojcius, David M., Jäättelä, Marja, Kroemer, Guido
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193790/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193790/

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