Two Distinct Pathways Leading to Nuclear Apoptosis
Apaf-1−/− or caspase-3−/− cells treated with a variety of apoptosis inducers manifest apoptosis-associated alterations including the translocation of apoptosis-inducing factor (AIF) from mitochondria to nuclei, large scale DNA fragmentation, and initial chromatin condensation (stage I). However, whe...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193229/ |