Conformational Requirements for Glycoprotein Reglucosylation in the Endoplasmic Reticulum
Newly synthesized glycoproteins interact during folding and quality control in the ER with calnexin and calreticulin, two lectins specific for monoglucosylated oligosaccharides. Binding and release are regulated by two enzymes, glucosidase II and UDP-Glc:glycoprotein:glycosyltransferase (GT), which...
Main Authors: | Trombetta, E. Sergio, Helenius, Ari |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174309/ |
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