Conformational Requirements for Glycoprotein Reglucosylation in the Endoplasmic Reticulum

Newly synthesized glycoproteins interact during folding and quality control in the ER with calnexin and calreticulin, two lectins specific for monoglucosylated oligosaccharides. Binding and release are regulated by two enzymes, glucosidase II and UDP-Glc:glycoprotein:glycosyltransferase (GT), which...

Full description

Bibliographic Details
Main Authors: Trombetta, E. Sergio, Helenius, Ari
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174309/