Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence

Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence

During biosynthesis, MHC class II-invariant chain complexes are transported into endosomal compartments where invariant chain (Ii) is degraded and class II encounters antigenic peptides. One of the signals that determines this intracellular transport route has been localized to the cytosolic domain...

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Bibliographic Details
Format:	Online
Language:	English
Published:	The Rockefeller University Press 1995
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120468/

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