Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules
We have studied the consequences of invariant chain (Ii) and DM expression on major histocompatibility complex (MHC) class II function. Ii has a number of discrete functions in the biology of class II, including competitive blocking of peptide binding in the endoplasmic reticulum and enhancing local...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1996
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192856/ |