Hla-Dm Recognizes the Flexible Conformation of Major Histocompatibility Complex Class II
DM facilitates formation of high affinity complexes of peptide–major histocompatibility complex (MHC) by release of class II MHC–associated invariant chain peptide (CLIP). This has been proposed to occur through discrimination of complex stability. By probing kinetic and conformational intermediates...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213500/ |