Hla-Dm Recognizes the Flexible Conformation of Major Histocompatibility Complex Class II

DM facilitates formation of high affinity complexes of peptide–major histocompatibility complex (MHC) by release of class II MHC–associated invariant chain peptide (CLIP). This has been proposed to occur through discrimination of complex stability. By probing kinetic and conformational intermediates...

Full description

Bibliographic Details
Main Authors: Chou, Chih-Ling, Sadegh-Nasseri, Scheherazade
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213500/