Dynamic interactions within sub-complexes of the H/ACA pseudouridylation guide RNP
H/ACA RNP complexes change uridines to pseudouridines in target non-coding RNAs in eukaryotes and archaea. H/ACA RNPs are comprised of a guide RNA and four essential proteins: Cbf5 (pseudouridine synthase), L7Ae, Gar1 and Nop10 in archaea. The guide RNA captures the target RNA via two antisense elem...
Main Authors: | Youssef, Osama A., Terns, Rebecca M., Terns, Michael P. |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094053/ |
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