DNA targeting by the type I-G and type I-A CRISPR–Cas systems of Pyrococcus furiosus
CRISPR–Cas systems silence plasmids and viruses in prokaryotes. CRISPR–Cas effector complexes contain CRISPR RNAs (crRNAs) that include sequences captured from invaders and direct CRISPR-associated (Cas) proteins to destroy corresponding invader nucleic acids. Pyrococcus furiosus (Pfu) harbors three...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666368/ |