Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis
We assessed viable Pax7 − / − mice in 129Sv/J background and observed reduced growth and marked muscle wasting together with a complete absence of functional satellite cells. Acute injury resulted in an extreme deficit in muscle regeneration. However, a small number of regenerated myofibers were det...
Main Authors: | Kuang, Shihuan, Chargé, Sophie B., Seale, Patrick, Huh, Michael, Rudnicki, Michael A. |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063538/ |
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