Pax7 Is Necessary and Sufficient for the Myogenic Specification of CD45+:Sca1+ Stem Cells from Injured Muscle
CD45+:Sca1+ adult stem cells isolated from uninjured muscle do not display any myogenic potential, whereas those isolated from regenerating muscle give rise to myoblasts expressing the paired-box transcription factor Pax7 and the bHLH factors Myf5 and MyoD. By contrast, CD45+:Sca1+ isolated from inj...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Public Library of Science
2004
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406392/ |