Binding Site Graphs: A New Graph Theoretical Framework for Prediction of Transcription Factor Binding Sites

Computational prediction of nucleotide binding specificity for transcription factors remains a fundamental and largely unsolved problem. Determination of binding positions is a prerequisite for research in gene regulation, a major mechanism controlling phenotypic diversity. Furthermore, an accurate...

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Bibliographic Details
Main Authors: Reddy, Timothy E, DeLisi, Charles, Shakhnovich, Boris E
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866359/