A Graph Based Framework to Model Virus Integration Sites

With next generation sequencing thousands of virus and viral vector integration genome targets are now under investigation to uncover specific integration preferences and to define clusters of integration, termed common integration sites (CIS), that may allow to assess gene therapy safety or to dete...

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Bibliographic Details
Main Authors: Fronza, Raffaele, Vasciaveo, Alessandro, Benso, Alfredo, Schmidt, Manfred
Format: Online
Language:English
Published: Research Network of Computational and Structural Biotechnology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874582/