Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABAA receptor subunit genes

Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABAA receptor subunit genes

Understanding transcription factor (TF) mediated control of gene expression remains a major challenge at the interface of computational and experimental biology. Computational techniques predicting TF-binding site specificity are frequently unreliable. On the other hand, comprehensive experimental v...

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Bibliographic Details
Main Authors: Reddy, Timothy E., Shakhnovich, Boris E., Roberts, Daniel S., Russek, Shelley J., DeLisi, Charles
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807961/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807961/

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