A graph-based motif detection algorithm models complex nucleotide dependencies in transcription factor binding sites

Given a set of known binding sites for a specific transcription factor, it is possible to build a model of the transcription factor binding site, usually called a motif model, and use this model to search for other sites that bind the same transcription factor. Typically, this search is performed us...

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Bibliographic Details
Main Authors: Naughton, Brian T., Fratkin, Eugene, Batzoglou, Serafim, Brutlag, Douglas L.
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635261/