A propofol binding site on mammalian GABAA receptors identified by photolabeling

A propofol binding site on mammalian GABAA receptors identified by photolabeling

Propofol is the most important intravenous general anesthetic in current clinical use. It acts by potentiating GABAA receptors, but where it binds to this receptor is not known and has been a matter of some controversy. We have synthesized a novel propofol analogue photolabeling reagent that has a b...

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Bibliographic Details
Main Authors: Yip, Grace M S, Chen, Zi-Wei, Edge, Christopher J, Smith, Edward H, Dickinson, Robert, Hohenester, Erhard, Townsend, R Reid, Fuchs, Karoline, Sieghart, Werner, Evers, Alex S, Franks, Nicholas P
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951778/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951778/

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