Binding Site Graphs: A New Graph Theoretical Framework for Prediction of Transcription Factor Binding Sites

by Reddy, Timothy E, DeLisi, Charles, Shakhnovich, Boris E
Published 2007

Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABAA receptor subunit genes

by Reddy, Timothy E., Shakhnovich, Boris E., Roberts, Daniel S., Russek, Shelley J., DeLisi, Charles
Published 2007

New Insights Into Gestational Glucose Metabolism: Lessons Learned From 21st Century Approaches

by Angueira, Anthony R., Ludvik, Anton E., Reddy, Timothy E., Wicksteed, Barton, Lowe, William L., Layden, Brian T.
Published 2015

Multiplex CRISPR/Cas9-Based Genome Editing for Correction of Dystrophin Mutations that Cause Duchenne Muscular Dystrophy

by Ousterout, David G., Kabadi, Ami M., Thakore, Pratiksha I., Majoros, William H., Reddy, Timothy E., Gersbach, Charles A.
Published 2015

Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation

by Gertz, Jason, Varley, Katherine E., Reddy, Timothy E., Bowling, Kevin M., Pauli, Florencia, Parker, Stephanie L., Kucera, Katerina S., Willard, Huntington F., Myers, Richard M.
Published 2011

Highly Specific Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements

by Thakore, Pratiksha I., D’Ippolito, Anthony M, Song, Lingyun, Safi, Alexias, Shivakumar, Nishkala K., Kabadi, Ami M., Reddy, Timothy E., Crawford, Gregory E., Gersbach, Charles A.
Published 2015

Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain

by Kabadi, Ami M., Thakore, Pratiksha I., Vockley, Christopher M., Ousterout, David G., Gibson, Tyler M., Guilak, Farshid, Reddy, Timothy E., Gersbach, Charles A.
Published 2014

Epigenome editing by a CRISPR/Cas9-based acetyltransferase activates genes from promoters and enhancers

by Hilton, Isaac B., D’Ippolito, Anthony M., Vockley, Christopher M., Thakore, Pratiksha I., Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Published 2015

Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases

by Ousterout, David G, Kabadi, Ami M, Thakore, Pratiksha I, Perez-Pinera, Pablo, Brown, Matthew T, Majoros, William H, Reddy, Timothy E, Gersbach, Charles A
Published 2015

Coordinated Regulatory Variation Associated with Gestational Hyperglycemia Regulates Expression of the Novel Hexokinase HKDC1

by Guo, Cong, Ludvik, Anton E., Arlotto, Michelle E., Hayes, M. Geoffrey, Armstrong, Loren L., Scholtens, Denise M., Brown, Christopher D., Newgard, Christopher B., Becker, Thomas C., Layden, Brian T., Lowe, William L., Reddy, Timothy E.
Published 2015

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

by Perez-Pinera, Pablo, Kocak, D. Dewran, Vockley, Christopher M., Adler, Andrew F., Kabadi, Ami M., Polstein, Lauren R., Thakore, Pratiksha I., Glass, Katherine A., Ousterout, David G., Leong, Kam W., Guilak, Farshid, Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Published 2013

Identification of HKDC1 and BACE2 as Genes Influencing Glycemic Traits During Pregnancy Through Genome-Wide Association Studies

by Hayes, M. Geoffrey, Urbanek, Margrit, Hivert, Marie-France, Armstrong, Loren L., Morrison, Jean, Guo, Cong, Lowe, Lynn P., Scheftner, Douglas A., Pluzhnikov, Anna, Levine, David M., McHugh, Caitlin P., Ackerman, Christine M., Bouchard, Luigi, Brisson, Diane, Layden, Brian T., Mirel, Daniel, Doheny, Kimberly F., Leya, Marysa V., Lown-Hecht, Rachel N., Dyer, Alan R., Metzger, Boyd E., Reddy, Timothy E., Cox, Nancy J., Lowe, William L.
Published 2013