Regulation of the differentiation of PC12 pheochromocytoma cells.
The PC12 clone, developed from a pheochromocytoma tumor of the rat adrenal medulla, has become a premiere model for the study of neuronal differentiation. When treated in culture with nanomolar concentrations of nerve growth factor, PC12 cells stop dividing, elaborate processes, become electrically...
Main Authors: | Fujita, K, Lazarovici, P, Guroff, G |
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Format: | Online |
Language: | English |
Published: |
1989
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567620/ |
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