Lithium Improves Survival of PC12 Pheochromocytoma Cells in High-Density Cultures and after Exposure to Toxic Compounds

Autophagy is an evolutionary conserved mechanism that allows for the degradation of long-lived proteins and entire organelles which are driven to lysosomes for digestion. Different kinds of stressful conditions such as starvation are able to induce autophagy. Lithium and rapamycin are potent autopha...

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Bibliographic Details
Main Authors: Fabrizi, Cinzia, De Vito, Stefania, Somma, Francesca, Pompili, Elena, Catizone, Angela, Leone, Stefano, Lenzi, Paola, Fornai, Francesco, Fumagalli, Lorenzo
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915898/