Changes in the colchicine susceptibility of microtubules associated with neurite outgrowth: studies with nerve growth factor-responsive PC12 pheochromocytoma cells

The PC12 line of nerve growth factor (NGF)-responsive rat pheochromocytoma cells was used as a model system to determine whether properties of microtubules change during neurite growth and maturation. In the absence of NGF, PC12 cells lack processes. After several days with NGF, PC12 cells begin ext...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1982
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112955/