Regulation of the differentiation of PC12 pheochromocytoma cells.

The PC12 clone, developed from a pheochromocytoma tumor of the rat adrenal medulla, has become a premiere model for the study of neuronal differentiation. When treated in culture with nanomolar concentrations of nerve growth factor, PC12 cells stop dividing, elaborate processes, become electrically...

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Bibliographic Details
Main Authors: Fujita, K, Lazarovici, P, Guroff, G
Format: Online
Language:English
Published: 1989
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567620/