Switchable synthesis of Z-homoallylic boronates and E-allylic boronates by enantioselective copper-catalyzed 1,6-boration
The enantioselective Cu-catalyzed 1,6-boration of (E,E) α,β,γ,δ-unsaturated ketones is described, which gives homoallylic boronates with high enantiomeric purity and unexpectedly high Zselectivity. By changing the solvent, the outcome can be altered to give E-allylic boronates.
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018
|
| Online Access: | http://eprints.nottingham.ac.uk/51268/ http://eprints.nottingham.ac.uk/51268/ http://eprints.nottingham.ac.uk/51268/ http://eprints.nottingham.ac.uk/51268/1/Hon%20Lam%20Switchable%20Synhesis%20of%20Z-Homoallylic.pdf |