Enantioselective nickel-catalyzed intramolecular allylic alkenylations enabled by reversible alkenylnickel E/Z isomerization
Enantioselective nickel-catalyzed arylative cyclizations of substrates containing a Z-allylic phosphate tethered to an alkyne are described. These reactions give multisubstituted chiral aza- and carbocycles, and are initiated by the addition of an arylboronic acid to the alkyne, followed by cyclizat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH Verlag
2017
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| Online Access: | http://eprints.nottingham.ac.uk/43683/ http://eprints.nottingham.ac.uk/43683/ http://eprints.nottingham.ac.uk/43683/ http://eprints.nottingham.ac.uk/43683/8/anie201703380.pdf |