Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels
The soluble cleaved urokinase plasminogen activator receptor (scuPAR) is a circulating protein detected in multiple diseases, including various cancers, cardiovascular disease, and kidney disease, where elevated levels of scuPAR have been associated with worsening prognosis and increased disease agg...
Main Authors: | Portelli, Michael, Siedlinski, Mateusz, Stewart, Ceri E., Postma, Dirkje S., Nieuwenhuis, Maartje A., Vonk, Judith M., Nurnberg, Peter, Altmuller, Janine, Moffatt, M.F., Wardlaw, Andrew J., Parker, Stuart G., Connolly, Martin J., Koppelman, Gerard H., Sayers, Ian |
---|---|
Format: | Article |
Language: | English |
Published: |
Federation of American Society of Experimental Biology
2014
|
Online Access: | http://eprints.nottingham.ac.uk/3171/ http://eprints.nottingham.ac.uk/3171/ http://eprints.nottingham.ac.uk/3171/ http://eprints.nottingham.ac.uk/3171/1/Portelli_Genome-wide_protein_QTL_mapping_identifies_human.pdf |
Similar Items
-
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels
by: Portelli, Michael A., et al.
Published: (2014) -
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels
by: Portelli, Michael A., et al.
Published: (2014) -
uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium
by: Stewart, Ceri E, et al.
Published: (2011) -
Response
by: Sayers, Ian, et al.
Published: (2015) -
uPAR's signaling two step
by: Leslie, Mitch
Published: (2007)