uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery

Pre- and intraoperative diagnostic techniques facilitating tumor staging are of paramount importance in colorectal cancer surgery. The urokinase receptor (uPAR) plays an important role in the development of cancer, tumor invasion, angiogenesis, and metastasis and over-expression is found in the majo...

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Bibliographic Details
Main Authors: Boonstra, Martin C., van Driel, Pieter B.A.A., van Willigen, Danny M., Stammes, Marieke A., Prevoo, Hendrica A.J.M., Tummers, Quirijn R.J.G., Mazar, Andrew P., Beekman, Freek J., Kuppen, Peter J.K., van de Velde, Cornelis J.H., Löwik, Clemens W.G.M., Frangioni, John V., van Leeuwen, Fijs W.B., Sier, Cornelis F.M., Vahrmeijer, Alexander L.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546465/