Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels

The soluble cleaved urokinase plasminogen activator receptor (scuPAR) is a circulating protein detected in multiple diseases, including various cancers, cardiovascular disease, and kidney disease, where elevated levels of scuPAR have been associated with worsening prognosis and increased disease agg...

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Bibliographic Details
Main Authors: Portelli, Michael A., Siedlinski, Mateusz, Stewart, Ceri E., Postma, Dirkje S., Nieuwenhuis, Maartje A., Vonk, Judith M., Nurnberg, Peter, Altmuller, Janine, Moffatt, M.F., Wardlaw, Andrew J., Parker, Stuart G., Connolly, Martin J., Koppelman, Gerard H., Sayers, Ian
Format: Article
Language:English
English
English
Published: Federation of American Society of Experimental Biology 2014
Online Access:http://eprints.nottingham.ac.uk/32639/
http://eprints.nottingham.ac.uk/32639/
http://eprints.nottingham.ac.uk/32639/
http://eprints.nottingham.ac.uk/32639/1/Portelli%20FASEB%20J%202014.pdf
http://eprints.nottingham.ac.uk/32639/2/Sayers%20FASEB%20SF1.pdf
http://eprints.nottingham.ac.uk/32639/3/Sayers%20FASEB%20Supplementary%20Figure%202.pdf