Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221

miR-221/-222 and components of the urokinase-type plasminogen activator system (uPAS) are associated with metastasis and poor prognosis in breast cancer, including the triple-negative subtype (TNBC). Modification of components of uPAS and involved miRNAs may contribute to targeted therapy for breast...

Full description

Bibliographic Details
Main Authors: Falkenberg, Natalie, Anastasov, NataĊĦa, Schaub, Annalisa, Radulovic, Vanja, Schmitt, Manfred, Magdolen, Viktor, Aubele, Michaela
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480738/