DNA Double Strand Break Response and Limited Repair Capacity in Mouse Elongated Spermatids

by Ahmed, Emad A., Scherthan, Harry, de Rooij, Dirk G.
Published 2015

Spermatid development in XO male mice with varying Y chromosome short-arm gene content: evidence for a Y gene controlling the initiation of sperm morphogenesis

by Vernet, Nadège, Mahadevaiah, Shantha K, Ellis, Peter J I, de Rooij, Dirk G, Burgoyne, Paul S
Published 2012

The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages

by Chi, Mai Nguyen, Auriol, Jacques, Jégou, Bernard, Kontoyiannis, Dimitris L., Turner, James M.A., de Rooij, Dirk G., Morello, Dominique
Published 2011

SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombination

by Bolcun-Filas, Ewelina, Costa, Yael, Speed, Robert, Taggart, Mary, Benavente, Ricardo, De Rooij, Dirk G, Cooke, Howard J
Published 2007

Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development

by Vernet, Nadege, Mahadevaiah, Shantha K., Decarpentrie, Fanny, Longepied, Guy, de Rooij, Dirk G., Burgoyne, Paul S., Mitchell, Michael J.
Published 2016

A Dominant, Recombination-Defective Allele of Dmc1 Causing Male-Specific Sterility

by Bannister, Laura A, Pezza, Roberto J, Donaldson, Janet R, de Rooij, Dirk G, Schimenti, Kerry J, Camerini-Otero, R. Daniel, Schimenti, John C
Published 2007

RSPO1/β-Catenin Signaling Pathway Regulates Oogonia Differentiation and Entry into Meiosis in the Mouse Fetal Ovary

by Chassot, Anne-Amandine, Gregoire, Elodie P., Lavery, Rowena, Taketo, Makoto M., de Rooij, Dirk G., Adams, Ian R., Chaboissier, Marie-Christine
Published 2011

Meiotic cohesin complexes are essential for the formation of the axial element in mice

by Llano, Elena, Herrán, Yurema, García-Tuñón, Ignacio, Gutiérrez-Caballero, Cristina, de Álava, Enrique, Barbero, José Luis, Schimenti, John, de Rooij, Dirk G., Sánchez-Martín, Manuel, Pendás, Alberto M.
Published 2012

Testicular Differentiation Occurs in Absence of R-spondin1 and Sox9 in Mouse Sex Reversals

by Lavery, Rowena, Chassot, Anne-Amandine, Pauper, Eva, Gregoire, Elodie P., Klopfenstein, Muriel, de Rooij, Dirk G., Mark, Manuel, Schedl, Andreas, Ghyselinck, Norbert B., Chaboissier, Marie-Christine
Published 2012

The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis

by Vlachogiannis, Georgios, Niederhuth, Chad E., Tuna, Salih, Stathopoulou, Athanasia, Viiri, Keijo, de Rooij, Dirk G., Jenner, Richard G., Schmitz, Robert J., Ooi, Steen K.T.
Published 2015

Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

by Luo, Mengcheng, Zhou, Jian, Leu, N. Adrian, Abreu, Carla M., Wang, Jianle, Anguera, Montserrat C., de Rooij, Dirk G., Jasin, Maria, Wang, P. Jeremy
Published 2015

shRNA Off-Target Effects In Vivo: Impaired Endogenous siRNA Expression and Spermatogenic Defects

by Song, Hye-Won, Bettegowda, Anilkumar, Oliver, Daniel, Yan, Wei, Phan, Mimi H., de Rooij, Dirk G., Corbett, Mark A., Wilkinson, Miles F.
Published 2015

A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11

by Faieta, Monica, Di Cecca, Stefano, de Rooij, Dirk G., Luchetti, Andrea, Murdocca, Michela, Di Giacomo, Monica, Di Siena, Sara, Pellegrini, Manuela, Rossi, Pellegrino, Barchi, Marco
Published 2015

UBR2 of the N-End Rule Pathway Is Required for Chromosome Stability via Histone Ubiquitylation in Spermatocytes and Somatic Cells

by An, Jee Young, Kim, Euna, Zakrzewska, Adriana, Yoo, Young Dong, Jang, Jun Min, Han, Dong Hoon, Lee, Min Jae, Seo, Jai Wha, Lee, Yong Jun, Kim, Tae-You, de Rooij, Dirk G., Kim, Bo Yeon, Kwon, Yong Tae
Published 2012

H2B ubiquitination regulates meiotic recombination by promoting chromatin relaxation

by Xu, Zhiliang, Song, Zhenhua, Li, Guoping, Tu, Huayu, Liu, Weixiao, Liu, Yujiao, Wang, Pan, Wang, Yuanting, Cui, Xiuhong, Liu, Chao, Shang, Yongliang, de Rooij, Dirk G., Gao, Fei, Li, Wei
Published 2016

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility

by Gómez-H, Laura, Felipe-Medina, Natalia, Sánchez-Martín, Manuel, Davies, Owen R., Ramos, Isabel, García-Tuñón, Ignacio, de Rooij, Dirk G., Dereli, Ihsan, Tóth, Attila, Barbero, José Luis, Benavente, Ricardo, Llano, Elena, Pendas, Alberto M.
Published 2016