H2B ubiquitination regulates meiotic recombination by promoting chromatin relaxation

H2B ubiquitination regulates meiotic recombination by promoting chromatin relaxation

Meiotic recombination is essential for fertility in most sexually reproducing species, but the molecular mechanisms underlying this process remain poorly understood in mammals. Here, we show that RNF20-mediated H2B ubiquitination is required for meiotic recombination. A germ cell-specific knockout o...

Full description

Bibliographic Details
Main Authors: Xu, Zhiliang, Song, Zhenhua, Li, Guoping, Tu, Huayu, Liu, Weixiao, Liu, Yujiao, Wang, Pan, Wang, Yuanting, Cui, Xiuhong, Liu, Chao, Shang, Yongliang, de Rooij, Dirk G., Gao, Fei, Li, Wei
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175339/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175339/

Similar Items