Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

Polycomb group proteins mediate transcriptional silencing in diverse developmental processes. Sex chromosomes undergo chromosome-wide transcription silencing during male meiosis. Here we report that mouse SCML2 (Sex comb on midleg-like 2), an X chromosome-encoded polycomb protein, is specifically ex...

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Bibliographic Details
Main Authors: Luo, Mengcheng, Zhou, Jian, Leu, N. Adrian, Abreu, Carla M., Wang, Jianle, Anguera, Montserrat C., de Rooij, Dirk G., Jasin, Maria, Wang, P. Jeremy
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310598/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310598/

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