A Dominant, Recombination-Defective Allele of Dmc1 Causing Male-Specific Sterility

A Dominant, Recombination-Defective Allele of Dmc1 Causing Male-Specific Sterility

DMC1 is a meiosis-specific homolog of bacterial RecA and eukaryotic RAD51 that can catalyze homologous DNA strand invasion and D-loop formation in vitro. DMC1-deficient mice and yeast are sterile due to defective meiotic recombination and chromosome synapsis. The authors identified a male dominant s...

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Bibliographic Details
Main Authors: Bannister, Laura A, Pezza, Roberto J, Donaldson, Janet R, de Rooij, Dirk G, Schimenti, Kerry J, Camerini-Otero, R. Daniel, Schimenti, John C
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847842/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847842/

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