In Vivo Cytotoxic T Lymphocyte Elicitation by Mycobacterial Heat Shock Protein 70 Fusion Proteins Maps to a Discrete Domain and Is Cd4+ T Cell Independent

by Huang, Qian, Richmond, Joan F.L., Suzue, Kimiko, Eisen, Herman N., Young, Richard A.
Published 2000

Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

by Mahony, Shaun, Mazzoni, Esteban O, McCuine, Scott, Young, Richard A, Wichterle, Hynek, Gifford, David K
Published 2011

Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements

by Dowen, Jill M., Bilodeau, Steve, Orlando, David A., Hübner, Michael R., Abraham, Brian J., Spector, David L., Young, Richard A.
Published 2013

Evidence That Gene Activation and Silencing during Stem Cell Differentiation Requires a Transcriptionally Paused Intermediate State

by Golob, Jonathan L., Kumar, Roshan M., Guenther, Matthew G., Pabon, Lil M., Pratt, Gabriel A., Loring, Jeanne F., Laurent, Louise C., Young, Richard A., Murry, Charles E.
Published 2011

Embryonic stem cell-based system for mapping developmental transcriptional programs

by Mazzoni, Esteban O., Mahony, Shaun, Iacovino, Michelina, Morrison, Carolyn A., Mountoufaris, George, Closser, Michael, Whyte, Warren A., Young, Richard A., Kyba, Michael, Gifford, David K., Wichterle, Hynek
Published 2011

Zebrafish promoter microarrays identify actively transcribed embryonic genes

by Wardle, Fiona C, Odom, Duncan T, Bell, George W, Yuan, Bingbing, Danford, Timothy W, Wiellette, Elizabeth L, Herbolsheimer, Elizabeth, Sive, Hazel L, Young, Richard A, Smith, James C
Published 2006

Core transcriptional regulatory circuitry in human hepatocytes

by Odom, Duncan T, Dowell, Robin D, Jacobsen, Elizabeth S, Nekludova, Lena, Rolfe, P Alexander, Danford, Timothy W, Gifford, David K, Fraenkel, Ernest, Bell, Graeme I, Young, Richard A
Published 2006

Saltatory remodeling of Hox chromatin in response to rostro-caudal patterning signals

by Mazzoni, Esteban O., Mahony, Shaun, Peljto, Mirza, Patel, Tulsi, Thornton, Seraphim R., McCuine, Scott, Reeder, Christopher, Boyer, Laurie A., Young, Richard A., Gifford, David K., Wichterle, Hynek
Published 2013

Parkinson-associated risk variant in enhancer element produces subtle effect on target gene expression

by Soldner, Frank, Stelzer, Yonatan, Shivalila, Chikdu S., Abraham, Brian J., Latourelle, Jeanne C., Barrasa, M. Inmaculada, Goldmann, Johanna, Myers, Richard H., Young, Richard A., Jaenisch, Rudolf
Published 2016

Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

by Cassady, John P., D’Alessio, Ana C., Sarkar, Sovan, Dani, Vardhan S., Fan, Zi Peng, Ganz, Kibibi, Roessler, Reinhard, Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf
Published 2014

Cell Cycle Genes Are the Evolutionarily Conserved Targets of the E2F4 Transcription Factor

by Conboy, Caitlin M., Spyrou, Christiana, Thorne, Natalie P., Wade, Elizabeth J., Barbosa-Morais, Nuno L., Wilson, Michael D., Bhattacharjee, Arindam, Young, Richard A., Tavaré, Simon, Lees, Jacqueline A., Odom, Duncan T.
Published 2007

The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia

by Mansour, Marc R., Sanda, Takaomi, Lawton, Lee N., Li, Xiaoyu, Kreslavsky, Taras, Novina, Carl D., Brand, Marjorie, Gutierrez, Alejandro, Kelliher, Michelle A., Jamieson, Catriona H.M., von Boehmer, Harald, Young, Richard A., Look, A. Thomas
Published 2013

A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity

by D’Alessio, Ana C., Fan, Zi Peng, Wert, Katherine J., Baranov, Petr, Cohen, Malkiel A., Saini, Janmeet S., Cohick, Evan, Charniga, Carol, Dadon, Daniel, Hannett, Nancy M., Young, Michael J., Temple, Sally, Jaenisch, Rudolf, Lee, Tong Ihn, Young, Richard A.
Published 2015

Genome-wide determination of drug localization

by Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J., Rahl, Peter B., Lovén, Jakob, Sigova, Alla A., Smith, William B., Lee, Tong Ihn, Bradner, James E., Young, Richard A.
Published 2013

The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma

by Ceol, Craig J., Houvras, Yariv, Jane-Valbuena, Judit, Bilodeau, Steve, Orlando, David A., Battisti, Valentine, Fritsch, Lauriane, Lin, William M., Hollmann, Travis J., Ferré, Fabrizio, Bourque, Caitlin, Burke, Christopher J., Turner, Laura, Uong, Audrey, Johnson, Laura A., Beroukhim, Rameen, Mermel, Craig H., Loda, Massimo, Ait-Si-Ali, Slimane, Garraway, Levi A., Young, Richard A., Zon, Leonard I.
Published 2011

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

by Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Published 2014

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

by Heyn, Holger, Vidal, Enrique, Ferreira, Humberto J., Vizoso, Miguel, Sayols, Sergi, Gomez, Antonio, Moran, Sebastian, Boque-Sastre, Raquel, Guil, Sonia, Martinez-Cardus, Anna, Lin, Charles Y., Royo, Romina, Sanchez-Mut, Jose V., Martinez, Ramon, Gut, Marta, Torrents, David, Orozco, Modesto, Gut, Ivo, Young, Richard A., Esteller, Manel
Published 2016

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

by Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Published 2014

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

by Kwiatkowski, Nicholas, Zhang, Tinghu, Rahl, Peter B, Abraham, Brian J, Reddy, Jessica, Ficarro, Scott B, Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Christopher R, Hannett, Nancy M, McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, Thomas, Mitsiades, Constantine, Weng, Andrew P, Brown, Jennifer R, Benes, Cyril H., Marto, Jarrod A, Young, Richard A, Gray, Nathanael S.
Published 2014

Response and resistance to BET bromodomain inhibitors in triple negative breast cancer

by Shu, Shaokun, Lin, Charles Y., He, Housheng Hansen, Witwicki, Robert M., Tabassum, Doris P., Roberts, Justin M., Janiszewska, Michalina, Huh, Sung Jin, Liang, Yi, Ryan, Jeremy, Doherty, Ernest, Mohammed, Hisham, Guo, Hao, Stover, Daniel G., Ekram, Muhammad B., Brown, Jonathan, D'Santos, Clive, Krop, Ian E., Dillon, Deborah, McKeown, Michael, Ott, Christopher, Qi, Jun, Ni, Min, Rao, Prakash K., Duarte, Melissa, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Anders, Lars, Young, Richard A., Winer, Eric, Letai, Antony, Barry, William T., Carroll, Jason S., Long, Henry, Brown, Myles, Liu, X. Shirley, Meyer, Clifford A., Bradner, James E., Polyak, Kornelia
Published 2016