Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

by Heyn, Holger, Vidal, Enrique, Ferreira, Humberto J., Vizoso, Miguel, Sayols, Sergi, Gomez, Antonio, Moran, Sebastian, Boque-Sastre, Raquel, Guil, Sonia, Martinez-Cardus, Anna, Lin, Charles Y., Royo, Romina, Sanchez-Mut, Jose V., Martinez, Ramon, Gut, Marta, Torrents, David, Orozco, Modesto, Gut, Ivo, Young, Richard A., Esteller, Manel
Published 2016

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 lysine 27 trimethylation

by Lane, Andrew A., Chapuy, Bjoern, Lin, Charles Y., Tivey, Trevor, Li, Hubo, Townsend, Elizabeth C., van Bodegom, Diederik, Day, Tovah A., Wu, Shuo-Chieh, Liu, Huiyun, Yoda, Akinori, Alexe, Gabriela, Schinzel, Anna C., Sullivan, Timothy J., Malinge, Sébastien, Taylor, Jordan E., Stegmaier, Kimberly, Jaffe, Jacob D., Bustin, Michael, te Kronnie, Geertruy, Izraeli, Shai, Harris, Marian, Stevenson, Kristen E., Neuberg, Donna, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Hahn, William C., Crispino, John D., Pellman, David, Weinstock, David M.
Published 2014

Response and resistance to BET bromodomain inhibitors in triple negative breast cancer

by Shu, Shaokun, Lin, Charles Y., He, Housheng Hansen, Witwicki, Robert M., Tabassum, Doris P., Roberts, Justin M., Janiszewska, Michalina, Huh, Sung Jin, Liang, Yi, Ryan, Jeremy, Doherty, Ernest, Mohammed, Hisham, Guo, Hao, Stover, Daniel G., Ekram, Muhammad B., Brown, Jonathan, D'Santos, Clive, Krop, Ian E., Dillon, Deborah, McKeown, Michael, Ott, Christopher, Qi, Jun, Ni, Min, Rao, Prakash K., Duarte, Melissa, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Anders, Lars, Young, Richard A., Winer, Eric, Letai, Antony, Barry, William T., Carroll, Jason S., Long, Henry, Brown, Myles, Liu, X. Shirley, Meyer, Clifford A., Bradner, James E., Polyak, Kornelia
Published 2016