Nitro drugs for the treatment of trypanosomatid diseases: past, present, and future prospects

by Patterson, Stephen, Wyllie, Susan
Published 2014

Methylglyoxal metabolism in trypanosomes and leishmania

by Wyllie, Susan, Fairlamb, Alan H.
Published 2011

Dissecting the Metabolic Roles of Pteridine Reductase 1 in Trypanosoma brucei and Leishmania major*

by Ong, Han B., Sienkiewicz, Natasha, Wyllie, Susan, Fairlamb, Alan H.
Published 2011

Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome

by Jones, Deuan C, Alphey, Magnus S, Wyllie, Susan, Fairlamb, Alan H
Published 2012

Biochemical and genetic characterization of Trypanosoma cruzi N-myristoyltransferase

by Roberts, Adam J., Torrie, Leah S., Wyllie, Susan, Fairlamb, Alan H.
Published 2014

Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy

by Ong, Han B, Sienkiewicz, Natasha, Wyllie, Susan, Patterson, Stephen, Fairlamb, Alan H
Published 2013

Allosteric Activation of Trypanosomatid Deoxyhypusine Synthase by a Catalytically Dead Paralog*♦

by Nguyen, Suong, Jones, Deuan C., Wyllie, Susan, Fairlamb, Alan H., Phillips, Margaret A.
Published 2013

Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei

by Ong, Han B, Lee, Wai S, Patterson, Stephen, Wyllie, Susan, Fairlamb, Alan H
Published 2015

Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei

by Wyllie, Susan, Foth, Bernardo J., Kelner, Anna, Sokolova, Antoaneta Y., Berriman, Matthew, Fairlamb, Alan H.
Published 2016

Visceral Leishmaniasis and Arsenic: An Ancient Poison Contributing to Antimonial Treatment Failure in the Indian Subcontinent?

by Perry, Meghan R., Wyllie, Susan, Prajapati, Vijay Kumar, Feldmann, Joerg, Sundar, Shyam, Boelaert, Marleen, Fairlamb, Alan H.
Published 2011

Norspermidine Is Not a Self-Produced Trigger for Biofilm Disassembly

by Hobley, Laura, Kim, Sok Ho, Maezato, Yukari, Wyllie, Susan, Fairlamb, Alan H., Stanley-Wall, Nicola R., Michael, Anthony J.
Published 2014

Activation of Bicyclic Nitro-drugs by a Novel Nitroreductase (NTR2) in Leishmania

by Wyllie, Susan, Roberts, Adam J., Norval, Suzanne, Patterson, Stephen, Foth, Bernardo J., Berriman, Matthew, Read, Kevin D., Fairlamb, Alan H.
Published 2016

The R Enantiomer of the Antitubercular Drug PA-824 as a Potential Oral Treatment for Visceral Leishmaniasis

by Patterson, Stephen, Wyllie, Susan, Stojanovski, Laste, Perry, Meghan R., Simeons, Frederick R. C., Norval, Suzanne, Osuna-Cabello, Maria, De Rycker, Manu, Read, Kevin D., Fairlamb, Alan H.
Published 2013

The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis

by Patterson, Stephen, Wyllie, Susan, Norval, Suzanne, Stojanovski, Laste, Simeons, Frederick RC, Auer, Jennifer L, Osuna-Cabello, Maria, Read, Kevin D, Fairlamb, Alan H
Published 2016

Quinol derivatives as potential trypanocidal agents

by Capes, Amy, Patterson, Stephen, Wyllie, Susan, Hallyburton, Irene, Collie, Iain T., McCarroll, Andrew J., Stevens, Malcolm F.G., Frearson, Julie A., Wyatt, Paul G., Fairlamb, Alan H., Gilbert, Ian H.
Published 2012

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

by Shameer, Sanu, Logan-Klumpler, Flora J., Vinson, Florence, Cottret, Ludovic, Merlet, Benjamin, Achcar, Fiona, Boshart, Michael, Berriman, Matthew, Breitling, Rainer, Bringaud, Frédéric, Bütikofer, Peter, Cattanach, Amy M., Bannerman-Chukualim, Bridget, Creek, Darren J., Crouch, Kathryn, de Koning, Harry P., Denise, Hubert, Ebikeme, Charles, Fairlamb, Alan H., Ferguson, Michael A. J., Ginger, Michael L., Hertz-Fowler, Christiane, Kerkhoven, Eduard J., Mäser, Pascal, Michels, Paul A. M., Nayak, Archana, Nes, David W., Nolan, Derek P., Olsen, Christian, Silva-Franco, Fatima, Smith, Terry K., Taylor, Martin C., Tielens, Aloysius G. M., Urbaniak, Michael D., van Hellemond, Jaap J., Vincent, Isabel M., Wilkinson, Shane R., Wyllie, Susan, Opperdoes, Fred R., Barrett, Michael P., Jourdan, Fabien
Published 2015