Signal integration in TGF-β, WNT, and Hippo pathways

by Attisano, Liliana, Wrana, Jeffrey L.
Published 2013

Looking into the Black Box: Insights into the Mechanisms of Somatic Cell Reprogramming

by David, Laurent, Samavarchi-Tehrani, Payman, Golipour, Azadeh, Wrana, Jeffrey L.
Published 2011

A critical role for NF2 and the Hippo pathway in branching morphogenesis

by Reginensi, Antoine, Enderle, Leonie, Gregorieff, Alex, Johnson, Randy L., Wrana, Jeffrey L., McNeill, Helen
Published 2016

A lateral signalling pathway coordinates shape volatility during cell migration

by Zhang, Liang, Luga, Valbona, Armitage, Sarah K., Musiol, Martin, Won, Amy, Yip, Christopher M., Plotnikov, Sergey V., Wrana, Jeffrey L.
Published 2016

A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening

by Jeon, Jouhyun, Nim, Satra, Teyra, Joan, Datti, Alessandro, Wrana, Jeffrey L, Sidhu, Sachdev S, Moffat, Jason, Kim, Philip M
Published 2014

Inhibition of SREBP1 sensitizes cells to death ligands

by Eberhard, Yanina, Gronda, Marcela, Hurren, Rose, Datti, Alessandro, MacLean, Neil, Ketela, Troy, Moffat, Jason, Wrana, Jeffrey L., Schimmer, Aaron D.
Published 2011

Evidence for Positive Selection on a Number of MicroRNA Regulatory Interactions during Recent Human Evolution

by Li, Jingjing, Liu, Yu, Xin, Xiaofeng, Kim, Taehyung Simon, Cabeza, Eduardo Aguiar, Ren, Jie, Nielsen, Rasmus, Wrana, Jeffrey L., Zhang, Zhaolei
Published 2012

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog - dependent cerebellar granule neuron progenitor cells and medulloblastoma cells

by Dey, Abhinav, Robitaille, Mélanie, Remke, Marc, Maier, Caroline, Malhotra, Anshu, Gregorieff, Alex, Wrana, Jeffrey L, Taylor, Michael D, Angers, Stéphane, Kenney, Anna Marie
Published 2016

Image-Based Genome-Wide siRNA Screen Identifies Selective Autophagy Factors

by Orvedahl, Anthony, Sumpter, Rhea, Xiao, Guanghua, Ng, Aylwin, Zou, Zhongju, Tang, Yi, Narimatsu, Masahiro, Gilpin, Christopher, Sun, Qihua, Roth, Michael, Forst, Christian V., Wrana, Jeffrey L., Zhang, Ying E., Luby-Phelps, Katherine, Xavier, Ramnik, Xie, Yang, Levine, Beth
Published 2011

PTEN regulates cilia through Dishevelled

by Shnitsar, Iryna, Bashkurov, Mikhail, Masson, Glenn R., Ogunjimi, Abiodun A., Mosessian, Sherly, Cabeza, Eduardo Aguiar, Hirsch, Calley L., Trcka, Daniel, Gish, Gerald, Jiao, Jing, Wu, Hong, Winklbauer, Rudolf, Williams, Roger L., Pelletier, Laurence, Wrana, Jeffrey L., Barrios-Rodiles, Miriam
Published 2015

Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways

by Abou El Hassan, Mohamed, Huang, Katherine, Eswara, Manoja B. K., Zhao, Michael, Song, Lan, Yu, Tao, Liu, Yu, Liu, Jeffrey C., McCurdy, Sean, Ma, Anqi, Wither, Joan, Jin, Jian, Zacksenhaus, Eldad, Wrana, Jeffrey L., Bremner, Rod
Published 2015

Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens

by Smith, Kristen M, Datti, Alessandro, Fujitani, Mayumi, Grinshtein, Natalie, Zhang, Libo, Morozova, Olena, Blakely, Kim M, Rotenberg, Susan A, Hansford, Loen M, Miller, Freda D, Yeger, Herman, Irwin, Meredith S, Moffat, Jason, Marra, Marco A, Baruchel, Sylvain, Wrana, Jeffrey L, Kaplan, David R
Published 2010

Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network

by Cassar, Paul A, Carpenedo, Richard L, Samavarchi‐Tehrani, Payman, Olsen, Jonathan B, Park, Chang Jun, Chang, Wing Y, Chen, Zhaoyi, Choey, Chandarong, Delaney, Sean, Guo, Huishan, Guo, Hongbo, Tanner, R Matthew, Perkins, Theodore J, Tenenbaum, Scott A, Emili, Andrew, Wrana, Jeffrey L, Gibbings, Derrick, Stanford, William L
Published 2015