Inhibition of SREBP1 sensitizes cells to death ligands
Evasion of death receptor ligand-induced apoptosis contributs to cancer development and progression. To better understand mechanisms conferring resistance to death ligands, we screened an siRNA library to identify sequences that sensitize resistant cells to fas activating antibody (CH-11). From this...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Impact Journals LLC
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260812/ |