Tumour Suppressor Mechanisms in the Control of Chromosome Stability: Insights from BRCA2

by Venkitaraman, Ashok R.
Published 2014

Micro(mi) RNA-34a targets protein phosphatase (PP)1γ to regulate DNA damage tolerance

by Takeda, Yuko, Venkitaraman, Ashok R
Published 2015

Oncogenic KRAS triggers MAPK-dependent errors in mitosis and MYC-dependent sensitivity to anti-mitotic agents

by Perera, David, Venkitaraman, Ashok R.
Published 2016

Inhibition of Interleukin 7 Receptor Signaling by Antigen Receptor Assembly

by Smart, Fiona M., Venkitaraman, Ashok R.
Published 2000

A vertebrate N-end rule degron reveals that Orc6 is required in mitosis for daughter cell abscission

by Bernal, Juan A., Venkitaraman, Ashok R.
Published 2011

Maximizing the Biochemical Resolving Power of Fluorescence Microscopy

by Esposito, Alessandro, Popleteeva, Marina, Venkitaraman, Ashok R.
Published 2013

A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis

by Lee, MiYoung, Venkitaraman, Ashok R
Published 2014

Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

by Cassidy, Liam D., Liau, Siong-Seng, Venkitaraman, Ashok R.
Published 2013

A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei

by Mahen, Robert, Hattori, Hiroyoshi, Lee, Miyoung, Sharma, Pooja, Jeyasekharan, Anand D., Venkitaraman, Ashok R.
Published 2013

Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing

by Liang, Hongqing, Esposito, Alessandro, De, Siddharth, Ber, Suzan, Collin, Philippe, Surana, Uttam, Venkitaraman, Ashok R.
Published 2014

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

by Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.
Published 2015

p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response

by Hattori, Hiroyoshi, Janky, Rekin’s, Nietfeld, Wilfried, Aerts, Stein, Madan Babu, M, Venkitaraman, Ashok R
Published 2014

A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange

by Shivji, Mahmud K. K., Davies, Owen R., Savill, Jane M., Bates, Debbie L., Pellegrini, Luca, Venkitaraman, Ashok R.
Published 2006

Using a Fragment-Based Approach To Target Protein–Protein Interactions

by Scott, Duncan E, Ehebauer, Matthias T, Pukala, Tara, Marsh, May, Blundell, Tom L, Venkitaraman, Ashok R, Abell, Chris, Hyvönen, Marko
Published 2013

Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP

by Wickramasinghe, Vihandha O., Andrews, Robert, Ellis, Peter, Langford, Cordelia, Gurdon, John B., Stewart, Murray, Venkitaraman, Ashok R., Laskey, Ronald A.
Published 2014

High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy

by Short, Judith M., Liu, Yang, Chen, Shaoxia, Soni, Neelesh, Madhusudhan, Mallur S., Shivji, Mahmud K.K., Venkitaraman, Ashok R.
Published 2016

Interrogation of the Protein-Protein Interactions between Human BRCA2 BRC Repeats and RAD51 Reveals Atomistic Determinants of Affinity

by Cole, Daniel J., Rajendra, Eeson, Roberts-Thomson, Meredith, Hardwick, Bryn, McKenzie, Grahame J., Payne, Mike C., Venkitaraman, Ashok R., Skylaris, Chris-Kriton
Published 2011

From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1**

by Śledź, Paweł, Stubbs, Christopher J, Lang, Steffen, Yang, Yong-Qing, McKenzie, Grahame J, Venkitaraman, Ashok R, Hyvönen, Marko, Abell, Chris
Published 2011

Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength

by Wickramasinghe, Vihandha O., Gonzàlez-Porta, Mar, Perera, David, Bartolozzi, Arthur R., Sibley, Christopher R., Hallegger, Martina, Ule, Jernej, Marioni, John C., Venkitaraman, Ashok R.
Published 2015

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization

by Jeyasekharan, Anand D, Liu, Yang, Hattori, Hiroyoshi, Pisupati, Venkat, Jonsdottir, Asta Bjork, Rajendra, Eeson, Lee, Miyoung, Sundaramoorthy, Elayanambi, Schlachter, Simon, Kaminski, Clemens, Ofir-Rosenfeld, Yaara, Sato, Ko, Savill, Jane, Ayoub, Nabieh, Venkitaraman, Ashok R
Published 2013