A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis

Defects in the completion of cell division by cytokinesis have long been proposed to foster carcinogenesis by engendering chromosome instability, but few tumor suppressor mechanisms controlling this process have so far been identified. Here, we identify a carboxyl (C)-terminal region of the high-mob...

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Bibliographic Details
Main Authors: Lee, MiYoung, Venkitaraman, Ashok R
Format: Online
Language:English
Published: Taylor & Francis 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614378/