Reply: The role of DNAJB2 in amyotrophic lateral sclerosis

by Chen, Han-Jou, Shaw, Christopher E.
Published 2016

Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo☆

by Tripathi, Vineeta Bhasker, Baskaran, Pranetha, Shaw, Christopher E., Guthrie, Sarah
Published 2014

TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

by Scotter, Emma L., Chen, Han-Jou, Shaw, Christopher E.
Published 2015

Unpicking neurodegeneration in a dish with human pluripotent stem cells: One cell type at a time

by Bilican, Bilada, Serio, Andrea, Shaw, Christopher E, Maniatis, Tom, Chandran, Siddharthan
Published 2013

Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria

by Mórotz, Gábor M., De Vos, Kurt J., Vagnoni, Alessio, Ackerley, Steven, Shaw, Christopher E., Miller, Christopher C.J.
Published 2012

A clinical tool for predicting survival in ALS

by Knibb, Jonathan A, Keren, Noa, Kulka, Anna, Leigh, P Nigel, Martin, Sarah, Shaw, Christopher E, Tsuda, Miho, Al-Chalabi, Ammar
Published 2016

ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation

by King, Andrew, Troakes, Claire, Smith, Bradley, Nolan, Matthew, Curran, Olimpia, Vance, Caroline, Shaw, Christopher E., Al-Sarraj, Safa
Published 2015

Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease

by Niblock, Michael, Hortobágyi, Tibor, Troakes, Claire, Al-Sarraj, Safa, Spickett, Carl, Jones, Rebecca, Shaw, Christopher E., Gallo, Jean-Marc
Published 2016

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their...

by Gomez-Deza, Jorge, Lee, Youn-bok, Troakes, Claire, Nolan, Matthew, Al-Sarraj, Safa, Gallo, Jean-Marc, Shaw, Christopher E.
Published 2015

The risk to relatives of patients with sporadic amyotrophic lateral sclerosis

by Hanby, Martha F., Scott, Kirsten M., Scotton, William, Wijesekera, Lokesh, Mole, Thomas, Ellis, Catherine E., Nigel Leigh, P., Shaw, Christopher E., Al-Chalabi, Ammar
Published 2011

Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments

by Ackerley, Steven, Thornhill, Paul, Grierson, Andrew J., Brownlees, Janet, Anderton, Brian H., Leigh, P. Nigel, Shaw, Christopher E., Miller, Christopher C.J.
Published 2003

Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons

by Ackerley, Steven, Grierson, Andrew J., Brownlees, Janet, Thornhill, Paul, Anderton, Brian H., Leigh, P. Nigel, Shaw, Christopher E., Miller, Christopher C.J.
Published 2000

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

by De Vos, Kurt J., Mórotz, Gábor M., Stoica, Radu, Tudor, Elizabeth L., Lau, Kwok-Fai, Ackerley, Steven, Warley, Alice, Shaw, Christopher E., Miller, Christopher C.J.
Published 2012

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

by Devlin, Anna-Claire, Burr, Karen, Borooah, Shyamanga, Foster, Joshua D., Cleary, Elaine M., Geti, Imbisaat, Vallier, Ludovic, Shaw, Christopher E., Chandran, Siddharthan, Miles, Gareth B.
Published 2015

U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish

by Yu, Yong, Chi, Binkai, Xia, Wei, Gangopadhyay, Jaya, Yamazaki, Tomohiro, Winkelbauer-Hurt, Marlene E., Yin, Shanye, Eliasse, Yoan, Adams, Edward, Shaw, Christopher E., Reed, Robin
Published 2015

The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis

by Chen, Han-Jou, Mitchell, Jacqueline C., Novoselov, Sergey, Miller, Jack, Nishimura, Agnes L., Scotter, Emma L., Vance, Caroline A., Cheetham, Michael E., Shaw, Christopher E.
Published 2016

A proposed staging system for amyotrophic lateral sclerosis

by Roche, Jose C., Rojas-Garcia, Ricardo, Scott, Kirsten M., Scotton, William, Ellis, Catherine E., Burman, Rachel, Wijesekera, Lokesh, Turner, Martin R., Leigh, P. Nigel, Shaw, Christopher E., Al-Chalabi, Ammar
Published 2012

Characterising the RNA targets and position-dependent splicing regulation by TDP-43; implications for neurodegenerative diseases

by Tollervey, James R., Curk, Tomaž, Rogelj, Boris, Briese, Michael, Cereda, Matteo, Kayikci, Melis, Hortobágyi, Tibor, Nishimura, Agnes L., Župunski, Vera, Patani, Rickie, Chandran, Siddharthan, Rot, Gregor, Zupan, Blaž, Shaw, Christopher E., Ule, Jernej
Published 2011

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

by Rogelj, Boris, Easton, Laura E., Bogu, Gireesh K., Stanton, Lawrence W., Rot, Gregor, Curk, Tomaž, Zupan, Blaž, Sugimoto, Yoichiro, Modic, Miha, Haberman, Nejc, Tollervey, James, Fujii, Ritsuko, Takumi, Toru, Shaw, Christopher E., Ule, Jernej
Published 2012

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

by Vance, Caroline, Scotter, Emma L., Nishimura, Agnes L., Troakes, Claire, Mitchell, Jacqueline C., Kathe, Claudia, Urwin, Hazel, Manser, Catherine, Miller, Christopher C., Hortobágyi, Tibor, Dragunow, Mike, Rogelj, Boris, Shaw, Christopher E.
Published 2013