A Human Challenge Model for Mycobacterium tuberculosis Using Mycobacterium bovis Bacille Calmette-Guérin

by Minassian, Angela M., Satti, Iman, Poulton, Ian D., Meyer, Joel, Hill, Adrian V. S., McShane, Helen
Published 2012

Gene Expression and Cytokine Profile Correlate With Mycobacterial Growth in a Human BCG Challenge Model

by Matsumiya, Magali, Satti, Iman, Chomka, Agnieszka, Harris, Stephanie A., Stockdale, Lisa, Meyer, Joel, Fletcher, Helen A., McShane, Helen
Published 2015

Evaluation of a Human BCG Challenge Model to Assess Antimycobacterial Immunity Induced by BCG and a Candidate Tuberculosis Vaccine, MVA85A, Alone and in Combination

by Harris, Stephanie A., Meyer, Joel, Satti, Iman, Marsay, Leanne, Poulton, Ian D., Tanner, Rachel, Minassian, Angela M., Fletcher, Helen A., McShane, Helen
Published 2014

Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity

by Minhinnick, Alice, Harris, Stephanie, Wilkie, Morven, Peter, Jonathan, Stockdale, Lisa, Manjaly-Thomas, Zita-Rose, Vermaak, Samantha, Satti, Iman, Moss, Paul, McShane, Helen
Published 2016

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response

by Matsumiya, Magali, Harris, Stephanie A, Satti, Iman, Stockdale, Lisa, Tanner, Rachel, O’Shea, Matthew K, Tameris, Michelle, Mahomed, Hassan, Hatherill, Mark, Scriba, Thomas J, Hanekom, Willem A, McShane, Helen, Fletcher, Helen A
Published 2014

Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines

by Smith, Steven G., Smits, Kaatje, Joosten, Simone A., van Meijgaarden, Krista E., Satti, Iman, Fletcher, Helen A., Caccamo, Nadia, Dieli, Francesco, Mascart, Francoise, McShane, Helen, Dockrell, Hazel M., Ottenhoff, Tom H. M.
Published 2015

A first-in-human phase 1 trial to evaluate the safety and immunogenicity of the candidate tuberculosis vaccine MVA85A-IMX313, administered to BCG-vaccinated adults

by Minhinnick, Alice, Satti, Iman, Harris, Stephanie, Wilkie, Morven, Sheehan, Sharon, Stockdale, Lisa, Thomas, Zita-Rose Manjaly, Lopez-Ramon, Raquel, Poulton, Ian, Lawrie, Alison, Vermaak, Samantha, Le Vert, Alexandre, Del Campo, Judith, Hill, Fergal, Moss, Paul, McShane, Helen
Published 2016

Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial

by Satti, Iman, Meyer, Joel, Harris, Stephanie A, Thomas, Zita-Rose Manjaly, Griffiths, Kristin, Antrobus, Richard D, Rowland, Rosalind, Ramon, Raquel Lopez, Smith, Mary, Sheehan, Sharon, Bettinson, Henry, McShane, Helen
Published 2014

Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A

by Harris, Stephanie A., Satti, Iman, Matsumiya, Magali, Stockdale, Lisa, Chomka, Agnieszka, Tanner, Rachel, O'Shea, Matthew K., Manjaly Thomas, Zita-Rose, Tameris, Michele, Mahomed, Hassan, Scriba, Thomas J., Hanekom, Willem A., Fletcher, Helen A., McShane, Helen
Published 2014

Safety and immunogenicity of an FP9-vectored candidate tuberculosis vaccine (FP85A), alone and with candidate vaccine MVA85A in BCG-vaccinated healthy adults: A phase I clinical tr...

by Rowland, Rosalind, Pathan, Ansar A., Satti, Iman, Poulton, Ian D., Matsumiya, Magali M. L., Whittaker, Megan, Minassian, Angela M., O’Hara, Geraldine A., Hamill, Matthew, Scott, Janet T., Harris, Stephanie A., Poyntz, Hazel C., Bateman, Cynthia, Meyer, Joel, Williams, Nicola, Gilbert, Sarah C., Lawrie, Alison M., Hill, Adrian V.S., McShane, Helen
Published 2013

A Phase I, Open-Label Trial, Evaluating the Safety and Immunogenicity of Candidate Tuberculosis Vaccines AERAS-402 and MVA85A, Administered by Prime-Boost Regime in BCG-Vaccinated...

by Sheehan, Sharon, Harris, Stephanie A., Satti, Iman, Hokey, David A., Dheenadhayalan, Veerabadran, Stockdale, Lisa, Manjaly Thomas, Zita-Rose, Minhinnick, Alice, Wilkie, Morven, Vermaak, Samantha, Meyer, Joel, O’Shea, Matthew K., Pau, Maria Grazia, Versteege, Isabella, Douoguih, Macaya, Hendriks, Jenny, Sadoff, Jerald, Landry, Bernard, Moss, Paul, McShane, Helen
Published 2015

Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial

by Ndiaye, Birahim Pierre, Thienemann, Friedrich, Ota, Martin, Landry, Bernard S, Camara, Makhtar, Dièye, Siry, Dieye, Tandakha Ndiaye, Esmail, Hanif, Goliath, Rene, Huygen, Kris, January, Vanessa, Ndiaye, Ibrahima, Oni, Tolu, Raine, Michael, Romano, Marta, Satti, Iman, Sutton, Sharon, Thiam, Aminata, Wilkinson, Katalin A, Mboup, Souleymane, Wilkinson, Robert J, McShane, Helen
Published 2015

A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults

by Minassian, Angela M, Rowland, Rosalind, Beveridge, Natalie E R, Poulton, Ian D, Satti, Iman, Harris, Stephanie, Poyntz, Hazel, Hamill, Matthew, Griffiths, Kristin, Sander, Clare R, Ambrozak, David R, Price, David A, Hill, Brenna J, Casazza, Joseph P, Douek, Daniel C, Koup, Richard A, Roederer, Mario, Winston, Alan, Ross, Jonathan, Sherrard, Jackie, Rooney, Guy, Williams, Nicola, Lawrie, Alison M, Fletcher, Helen A, Pathan, Ansar A, McShane, Helen
Published 2011

Corrigendum: T-cell activation is an immune correlate of risk in BCG vaccinated infants

by Fletcher, Helen A., Snowden, Margaret A., Landry, Bernard, Rida, Wasima, Satti, Iman, Harris, Stephanie A., Matsumiya, Magali, Tanner, Rachel, O'Shea, Matthew K., Dheenadhayalan, Veerabadran, Bogardus, Leah, Stockdale, Lisa, Marsay, Leanne, Chomka, Agnieszka, Harrington-Kandt, Rachel, Manjaly-Thomas, Zita-Rose, Naranbhai, Vivek, Stylianou, Elena, Darboe, Fatoumatta, Penn-Nicholson, Adam, Nemes, Elisa, Hatherill, Mark, Hussey, Gregory, Mahomed, Hassan, Tameris, Michele, McClain, J. Bruce, Evans, Thomas G., Hanekom, Willem A., Scriba, Thomas J., McShane, Helen
Published 2016

T-cell activation is an immune correlate of risk in BCG vaccinated infants

by Fletcher, Helen A., Snowden, Margaret A., Landry, Bernard, Rida, Wasima, Satti, Iman, Harris, Stephanie A., Matsumiya, Magali, Tanner, Rachel, O'Shea, Matthew K., Dheenadhayalan, Veerabadran, Bogardus, Leah, Stockdale, Lisa, Marsay, Leanne, Chomka, Agnieszka, Harrington-Kandt, Rachel, Manjaly-Thomas, Zita-Rose, Naranbhai, Vivek, Stylianou, Elena, Darboe, Fatoumatta, Penn-Nicholson, Adam, Nemes, Elisa, Hatherill, Mark, Hussey, Gregory, Mahomed, Hassan, Tameris, Michele, McClain, J Bruce, Evans, Thomas G., Hanekom, Willem A., Scriba, Thomas J., McShane, Helen
Published 2016