Evaluation of a Human BCG Challenge Model to Assess Antimycobacterial Immunity Induced by BCG and a Candidate Tuberculosis Vaccine, MVA85A, Alone and in Combination

Evaluation of a Human BCG Challenge Model to Assess Antimycobacterial Immunity Induced by BCG and a Candidate Tuberculosis Vaccine, MVA85A, Alone and in Combination

Background. A new vaccine is urgently needed to combat tuberculosis. However, without a correlate of protection, selection of the vaccines to take forward into large-scale efficacy trials is difficult. Use of bacille Calmette-Guérin (BCG) as a surrogate for human Mycobacterium tuberculosis challenge...

Full description

Bibliographic Details
Main Authors: Harris, Stephanie A., Meyer, Joel, Satti, Iman, Marsay, Leanne, Poulton, Ian D., Tanner, Rachel, Minassian, Angela M., Fletcher, Helen A., McShane, Helen
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969545/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969545/

Similar Items