Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity

Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity

Background. There is an urgent need for an improved tuberculosis vaccine. The lack of a validated correlate of protection slows progress in achieving this goal. A human mycobacterial challenge model, using bacille Calmette-Guérin (BCG) as a surrogate for a Mycobacterium tuberculosis challenge, would...

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Bibliographic Details
Main Authors: Minhinnick, Alice, Harris, Stephanie, Wilkie, Morven, Peter, Jonathan, Stockdale, Lisa, Manjaly-Thomas, Zita-Rose, Vermaak, Samantha, Satti, Iman, Moss, Paul, McShane, Helen
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747614/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747614/

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