Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A

The first phase IIb safety and efficacy trial of a new tuberculosis vaccine since that for BCG was completed in October 2012. BCG-vaccinated South African infants were randomized to receive modified vaccinia virus Ankara, expressing the Mycobacterium tuberculosis antigen 85A (MVA85A), or placebo. MV...

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Bibliographic Details
Main Authors: Harris, Stephanie A., Satti, Iman, Matsumiya, Magali, Stockdale, Lisa, Chomka, Agnieszka, Tanner, Rachel, O'Shea, Matthew K., Manjaly Thomas, Zita-Rose, Tameris, Michele, Mahomed, Hassan, Scriba, Thomas J., Hanekom, Willem A., Fletcher, Helen A., McShane, Helen
Format: Online
Language:English
Published: American Society for Microbiology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097435/