In vivo evidence for mTORC2-mediated actin cytoskeleton rearrangement in neurons

by Angliker, Nico, Rüegg, Markus A
Published 2013

Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-α2-deficient congenital muscular dystrophy (MDC1A)

by Meinen, Sarina, Lin, Shuo, Ruegg, Markus A
Published 2012

Fatigue and Muscle Atrophy in a Mouse Model of Myasthenia Gravis Is Paralleled by Loss of Sarcolemmal nNOS

by Meinen, Sarina, Lin, Shuo, Rüegg, Markus A., Punga, Anna Rostedt
Published 2012

Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors

by Camilleri, Alain A, Willmann, Raffaella, Sadasivam, Gayathri, Lin, Shuo, Rüegg, Markus A, Gesemann, Matthias, Fuhrer, Christian
Published 2007

Agrin Binds to the Nerve–Muscle Basal Lamina via Laminin

by Denzer, Alain J., Brandenberger, Ralph, Gesemann, Matthias, Chiquet, Matthias, Ruegg, Markus A.
Published 1997

Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice

by Meinen, Sarina, Lin, Shuo, Thurnherr, Raphael, Erb, Michael, Meier, Thomas, Rüegg, Markus A
Published 2011

Linker molecules between laminins and dystroglycan ameliorate laminin-α2–deficient muscular dystrophy at all disease stages

by Meinen, Sarina, Barzaghi, Patrizia, Lin, Shuo, Lochmüller, Hanns, Ruegg, Markus A.
Published 2007

Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism

by Guridi, Maitea, Kupr, Barbara, Romanino, Klaas, Lin, Shuo, Falcetta, Denis, Tintignac, Lionel, Rüegg, Markus A.
Published 2016

The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions

by Steiner, Esther, Enzmann, Gaby U., Lyck, Ruth, Lin, Shuo, Rüegg, Markus A., Kröger, Stephan, Engelhardt, Britta
Published 2014

Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology

by Thomanetz, Venus, Angliker, Nico, Cloëtta, Dimitri, Lustenberger, Regula M., Schweighauser, Manuel, Oliveri, Filippo, Suzuki, Noboru, Rüegg, Markus A.
Published 2013

Injection of a Soluble Fragment of Neural Agrin (NT-1654) Considerably Improves the Muscle Pathology Caused by the Disassembly of the Neuromuscular Junction

by Hettwer, Stefan, Lin, Shuo, Kucsera, Stefan, Haubitz, Monika, Oliveri, Filippo, Fariello, Ruggero G., Ruegg, Markus A., Vrijbloed, Jan W.
Published 2014

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation

by Ding, Xiaolei, Bloch, Wilhelm, Iden, Sandra, Rüegg, Markus A., Hall, Michael N., Leptin, Maria, Partridge, Linda, Eming, Sabine A.
Published 2016

The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory

by Reinhard, Judith R., Kriz, Alexander, Galic, Milos, Angliker, Nico, Rajalu, Mathieu, Vogt, Kaspar E., Ruegg, Markus A.
Published 2016

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy

by Bentzinger, C Florian, Lin, Shuo, Romanino, Klaas, Castets, Perrine, Guridi, Maitea, Summermatter, Serge, Handschin, Christoph, Tintignac, Lionel A, Hall, Michael N, Rüegg, Markus A
Published 2013

WNT7B Promotes Bone Formation in part through mTORC1

by Chen, Jianquan, Tu, Xiaolin, Esen, Emel, Joeng, Kyu Sang, Lin, Congxin, Arbeit, Jeffrey M., Rüegg, Markus A., Hall, Michael N., Ma, Liang, Long, Fanxin
Published 2014

Mesoangioblast delivery of miniagrin ameliorates murine model of merosin-deficient congenital muscular dystrophy type 1A

by Domi, Teuta, Porrello, Emanuela, Velardo, Daniele, Capotondo, Alessia, Biffi, Alessandra, Tonlorenzi, Rossana, Amadio, Stefano, Ambrosi, Alessandro, Miyagoe-Suzuki, Yuko, Takeda, Shin’ichi, Ruegg, Markus A., Previtali, Stefano Carlo
Published 2015

Neuropathology in Mice Expressing Mouse Alpha-Synuclein

by Rieker, Claus, Dev, Kumlesh K., Lehnhoff, Katja, Barbieri, Samuel, Ksiazek, Iwona, Kauffmann, Sabine, Danner, Simone, Schell, Heinrich, Boden, Cindy, Ruegg, Markus A., Kahle, Philipp J., van der Putten, Herman, Shimshek, Derya R.
Published 2011

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

by Kleinert, Maximilian, Sylow, Lykke, Fazakerley, Daniel J., Krycer, James R., Thomas, Kristen C., Oxbøll, Anne-Julie, Jordy, Andreas B., Jensen, Thomas E., Yang, Guang, Schjerling, Peter, Kiens, Bente, James, David E., Ruegg, Markus A., Richter, Erik A.
Published 2014

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

by Kleinert, Maximilian, Parker, Benjamin L., Chaudhuri, Rima, Fazakerley, Daniel J., Serup, Annette, Thomas, Kristen C., Krycer, James R., Sylow, Lykke, Fritzen, Andreas M., Hoffman, Nolan J., Jeppesen, Jacob, Schjerling, Peter, Ruegg, Markus A., Kiens, Bente, James, David E., Richter, Erik A.
Published 2016