mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation

Mammalian target of rapamycin (mTOR), a regulator of growth in many tissues, mediates its activity through two multiprotein complexes, mTORC1 or mTORC2. The role of mTOR signalling in skin morphogenesis and epidermal development is unknown. Here we identify mTOR as an essential regulator in skin mor...

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Bibliographic Details
Main Authors: Ding, Xiaolei, Bloch, Wilhelm, Iden, Sandra, Rüegg, Markus A., Hall, Michael N., Leptin, Maria, Partridge, Linda, Eming, Sabine A.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095294/