Agrin Binds to the Nerve–Muscle Basal Lamina via Laminin
Agrin is a heparan sulfate proteoglycan that is required for the formation and maintenance of neuromuscular junctions. During development, agrin is secreted from motor neurons to trigger the local aggregation of acetylcholine receptors (AChRs) and other proteins in the muscle fiber, which together c...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1997
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139873/ |