In vivo evidence for mTORC2-mediated actin cytoskeleton rearrangement in neurons

The mammalian target of rapamycin (mTOR) assembles into two distinct multi-protein complexes called mTORC1 and mTORC2. While mTORC1 controls the signaling pathways important for cell growth, the physiological function of mTORC2 is only partially known. Here we comment on recent work on gene-targeted...

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Bibliographic Details
Main Authors: Angliker, Nico, Rüegg, Markus A
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201605/