Multiscale Model of Colorectal Cancer Using the Cellular Potts Framework

by Osborne, James M
Published 2015

Eastern Mediterranean Economic Exchange during the Iron Age: Portable X-Ray Fluorescence and Neutron Activation Analysis of Cypriot-Style Pottery in the Amuq Valley, Turkey

by Karacic, Steven, Osborne, James F.
Published 2016

Computational Models Reveal a Passive Mechanism for Cell Migration in the Crypt

by Dunn, Sara-Jane, Näthke, Inke S., Osborne, James M.
Published 2013

Computer Simulation, Visualization, and Image Processing of Cancer Data and Processes

by Johnson, David, Osborne, James, Wang, Zhihui, Marias, Kostas
Published 2016

The Free Energy Landscape of Dimerization of a Membrane Protein, NanC

by Dunton, Thomas A., Goose, Joseph E., Gavaghan, David J., Sansom, Mark S. P., Osborne, James M.
Published 2014

CoGNaC: A Chaste Plugin for the Multiscale Simulation of Gene Regulatory Networks Driving the Spatial Dynamics of Tissues and Cancer

by Rubinacci, Simone, Graudenzi, Alex, Caravagna, Giulio, Mauri, Giancarlo, Osborne, James, Pitt-Francis, Joe, Antoniotti, Marco
Published 2015

Mechano-logical model of C. elegans germ line suggests feedback on the cell cycle

by Atwell, Kathryn, Qin, Zhao, Gavaghan, David, Kugler, Hillel, Hubbard, E. Jane Albert, Osborne, James M.
Published 2015

Sicily statement on evidence-based practice

by Dawes, Martin, Summerskill, William, Glasziou, Paul, Cartabellotta, Antonino, Martin, Janet, Hopayian, Kevork, Porzsolt, Franz, Burls, Amanda, Osborne, James
Published 2005

A Two-Dimensional Model of the Colonic Crypt Accounting for the Role of the Basement Membrane and Pericryptal Fibroblast Sheath

by Dunn, Sara-Jane, Appleton, Paul L., Nelson, Scott A., Näthke, Inke S., Gavaghan, David J., Osborne, James M.
Published 2012

Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche

by Langlands, Alistair J., Almet, Axel A., Appleton, Paul L., Newton, Ian P., Osborne, James M., Näthke, Inke S.
Published 2016

Ten Simple Rules for Effective Computational Research

by Osborne, James M., Bernabeu, Miguel O., Bruna, Maria, Calderhead, Ben, Cooper, Jonathan, Dalchau, Neil, Dunn, Sara-Jane, Fletcher, Alexander G., Freeman, Robin, Groen, Derek, Knapp, Bernhard, McInerny, Greg J., Mirams, Gary R., Pitt-Francis, Joe, Sengupta, Biswa, Wright, David W., Yates, Christian A., Gavaghan, David J., Emmott, Stephen, Deane, Charlotte
Published 2014

Chaste: An Open Source C++ Library for Computational Physiology and Biology

by Mirams, Gary R., Arthurs, Christopher J., Bernabeu, Miguel O., Bordas, Rafel, Cooper, Jonathan, Corrias, Alberto, Davit, Yohan, Dunn, Sara-Jane, Fletcher, Alexander G., Harvey, Daniel G., Marsh, Megan E., Osborne, James M., Pathmanathan, Pras, Pitt-Francis, Joe, Southern, James, Zemzemi, Nejib, Gavaghan, David J.
Published 2013

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eμ-MYC driven B-cell lymphoma

by Walton, Mike I., Eve, Paul D., Hayes, Angela, Henley, Alan T., Valenti, Melanie R., De Haven Brandon, Alexis K., Box, Gary, Boxall, Kathy J., Tall, Matthew, Swales, Karen, Matthews, Thomas P., McHardy, Tatiana, Lainchbury, Michael, Osborne, James, Hunter, Jill E., Perkins, Neil D., Aherne, G. Wynne, Reader, John C., Raynaud, Florence I., Eccles, Suzanne A., Collins, Ian, Garrett, Michelle D.
Published 2015

A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms

by Jones, Alan M., Westwood, Isaac M., Osborne, James D., Matthews, Thomas P., Cheeseman, Matthew D., Rowlands, Martin G., Jeganathan, Fiona, Burke, Rosemary, Lee, Diane, Kadi, Nadia, Liu, Manjuan, Richards, Meirion, McAndrew, Craig, Yahya, Norhakim, Dobson, Sarah E., Jones, Keith, Workman, Paul, Collins, Ian, van Montfort, Rob L. M.
Published 2016

Ten Simple Rules for a Successful Cross-Disciplinary Collaboration

by Knapp, Bernhard, Bardenet, Rémi, Bernabeu, Miguel O., Bordas, Rafel, Bruna, Maria, Calderhead, Ben, Cooper, Jonathan, Fletcher, Alexander G., Groen, Derek, Kuijper, Bram, Lewis, Joanna, McInerny, Greg, Minssen, Timo, Osborne, James, Paulitschke, Verena, Pitt-Francis, Joe, Todoric, Jelena, Yates, Christian A., Gavaghan, David, Deane, Charlotte M.
Published 2015